Maintenance of a normal meal-induced decrease in plasma ghrelin levels in children with Prader-Willi syndrome.

@article{Bizzarri2004MaintenanceOA,
  title={Maintenance of a normal meal-induced decrease in plasma ghrelin levels in children with Prader-Willi syndrome.},
  author={Carla Bizzarri and Antonello Emilio Rigamonti and Germana Giannone and R Berardinelli and Silvano G. Cella and Marco Cappa and Eugenio E. M{\"u}ller},
  journal={Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme},
  year={2004},
  volume={36 3},
  pages={164-9}
}
Ghrelin is a 28-amino acid peptide recently identified in the stomach as the endogenous ligand for the growth hormone secretagogue receptor (GHS-R1a). Ghrelin is a potent stimulator of GH secretion. It was recently shown that circulating ghrelin levels in humans rise shortly before and fall shortly after every meal, and that ghrelin administration increases voluntary food intake. The hypothesis that ghrelin hypersecretion might contribute to genetic obesity has never been investigated. In this… CONTINUE READING

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