Maintenance of Mitochondrial Morphology by Autophagy and Its Role in High Glucose Effects on Chronological Lifespan of Saccharomyces cerevisiae

@inproceedings{AungHtut2013MaintenanceOM,
  title={Maintenance of Mitochondrial Morphology by Autophagy and Its Role in High Glucose Effects on Chronological Lifespan of Saccharomyces cerevisiae},
  author={May Thandar Aung-Htut and Yuen Ting Lam and Yu-Leng Lim and Mark Rinnerthaler and Cristy L. Gelling and Hongyuan Yang and Michael Breitenbach and Ian W. Dawes},
  booktitle={Oxidative medicine and cellular longevity},
  year={2013}
}
In Saccharomyces cerevisiae, mitochondrial morphology changes when cells are shifted between nonfermentative and fermentative carbon sources. Here, we show that cells of S. cerevisiae grown in different glucose concentrations display different mitochondrial morphologies. The morphology of mitochondria in the cells growing in 0.5% glucose was similar to that of mitochondria in respiring cells. However, the mitochondria of cells growing in higher glucose concentrations (2% and 4%) became… CONTINUE READING