Maintenance of Histocompatibility Polymorphisms

@article{Clarke1966MaintenanceOH,
  title={Maintenance of Histocompatibility Polymorphisms},
  author={Bryan Clarke and D. R. S. Kirby},
  journal={Nature},
  year={1966},
  volume={211},
  pages={999-1000}
}
THE transplantation antigens present a striking example of genetic polymorphism. Medawar1 has stated that “Although there are no factual grounds for supposing that antigenic diversity is anything but an unfortunate consequence of constitutional differences between individuals of a species, yet one is under some obligation to rack one's brains for evidence of any good it might conceivably do. Only thus can antigenic polymorphism be made genetically respectable”. Because during gestation the… CONTINUE READING