Maintenance Bacillus Calmette-Guerin for Ta T1 bladder tumors is not associated with increased toxicity: results from a European Organisation for Research and Treatment of Cancer Genito-Urinary Group Phase III Trial.

@article{Meijden2003MaintenanceBC,
  title={Maintenance Bacillus Calmette-Guerin for Ta T1 bladder tumors is not associated with increased toxicity: results from a European Organisation for Research and Treatment of Cancer Genito-Urinary Group Phase III Trial.},
  author={Adrian P M van der Meijden and Richard Joel Sylvester and Wim Oosterlinck and Wolfgang Hoeltl and Aldo Vittorio Bono},
  journal={European urology},
  year={2003},
  volume={44 4},
  pages={429-34}
}
OBJECTIVES After transurethral resection, the local and systemic side effects of Bacillus Calmette-Guerin (BCG) instillations were assessed during a 6-week induction course followed by 3 weekly maintenance instillations at 3, 6, 12, 18, 24, 30 and 36 months to determine if BCG toxicity increases over time. METHODS 487 patients who received BCG in a multicenter phase III trial were included. Side effects were divided into 5 different treatment periods: the first 6 weeks induction, months 3 and… CONTINUE READING

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