Maintaining embryonic stem cell pluripotency with Wnt signaling.

@article{Sokol2011MaintainingES,
  title={Maintaining embryonic stem cell pluripotency with Wnt signaling.},
  author={Sergei Y Sokol},
  journal={Development},
  year={2011},
  volume={138 20},
  pages={4341-50}
}
Wnt signaling pathways control lineage specification in vertebrate embryos and regulate pluripotency in embryonic stem (ES) cells, but how the balance between progenitor self-renewal and differentiation is achieved during axis specification and tissue patterning remains highly controversial. The context- and stage-specific effects of the different Wnt pathways produce complex and sometimes opposite outcomes that help to generate embryonic cell diversity. Although the results of recent studies… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 1 time over the past 90 days. VIEW TWEETS
81 Citations
134 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 81 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 134 references

, the molecular circuitry of pluripotency and nuclear reprogramming

  • K. F. Kelly, D. Y. Ng, G. Jayakumaran, G. A. Wood, H. Koide, B. W. Doble
  • 2011

Wnt proteins control the murine embryonic to epiblast stem cell transition

  • D. ten Berge, D. Kurek, R. Siu, R. Nusse
  • Nat . Cell Biol .
  • 2011

Similar Papers

Loading similar papers…