Maintaining cell depth viability: on the efficacy of a trimodal scaffold pore architecture and dynamic rotational culturing.

Tissue-engineering scaffold-based strategies have suffered from limited cell depth viability when cultured in vitro with viable cells typically existing at the fluid-scaffold interface. This is primarily believed to be due to the lack of nutrient delivery into and waste removal from the inner regions of the scaffold construct. This work focused on the… CONTINUE READING