Maintaining K+ balance on the low-Na+, high-K+ diet.

@article{Cornelius2016MaintainingKB,
  title={Maintaining K+ balance on the low-Na+, high-K+ diet.},
  author={Ryan J. Cornelius and Bangchen Wang and Jun Wang-France and Steven C. Sansom},
  journal={American journal of physiology. Renal physiology},
  year={2016},
  volume={310 7},
  pages={
          F581-F595
        }
}
A low-Na+, high-K+ diet (LNaHK) is considered a healthier alternative to the "Western" high-Na+ diet. Because the mechanism for K+ secretion involves Na+ reabsorptive exchange for secreted K+ in the distal nephron, it is not understood how K+ is eliminated with such low Na+ intake. Animals on a LNaHK diet produce an alkaline load, high urinary flows, and markedly elevated plasma ANG II and aldosterone levels to maintain their K+ balance. Recent studies have revealed a potential mechanism… CONTINUE READING
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