Maintaining Fluoroquinolone Class Efficacy: Review of Influencing Factors

  title={Maintaining Fluoroquinolone Class Efficacy: Review of Influencing Factors},
  author={William Michael Scheld},
  booktitle={Emerging infectious diseases},
Previous experience with antimicrobial resistance has emphasized the importance of appropriate stewardship of these pharmacotherapeutic agents. The introduction of fluoroquinolones provided potent new drugs directed primarily against gram-negative pathogens, while the newer members of this class demonstrate more activity against gram-positive species, including Streptococcus pneumoniae. Although these agents are clinically effective against a broad range of infectious agents, emergence of… CONTINUE READING

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