Maintaining Continuity through a Scientific Revolution

@article{Kingsland2007MaintainingCT,
  title={Maintaining Continuity through a Scientific Revolution},
  author={Sharon E. Kingsland},
  journal={Isis},
  year={2007},
  volume={98},
  pages={468 - 488}
}
A rereading of the American scientific literature on sex determination from 1902 to 1926 leads to a different understanding of the construction of the Mendelian‐chromosome theory after 1910. There was significant intellectual continuity, which has not been properly appreciated, underlying this scientific “revolution.” After reexamining the relationship between the ideas of key scientists, in particular Edmund B. Wilson and Thomas Hunt Morgan, I argue that, contrary to the historical literature… 

The Riddle of Sex: Biological Theories of Sexual Difference in the Early Twentieth-Century

This paper will illustrate how the older metabolic theory of sex was displaced when those who argued for the relatively newer theories of chromosomes and hormones gradually formed an alliance that accommodated each other and excluded the metabolic Theory of sex.

Thomas Hunt Morgan and the invisible gene: the right tool for the job

The paper analyzes the early theory building process of Thomas Hunt Morgan from the 1910s to the 1930s and the introduction of the invisible gene as a main explanatory unit of heredity and the continuity of the questions to be addressed by both embryology and genetics.

CROSSOVERS BETWEEN EPIGENESIS AND EPIGENETICS. A MULTICENTER APPROACH TO THE HISTORY OF EPIGENETICS (1901-1975).

The aim of the present paper is to reveal a hidden history of epigenetics, by means of a multicenter approach, and shows that genetics and embryology in early XX century--far from being non-communicating vessels--shared similar questions, as epitomized by Thomas Hunt Morgan's works.

Sex and Neo-Sex Chromosomes in Orthoptera: A Review*

The hypothesis that neo-sex chromosome systems produce favorable new linkage relationships between genes in the X and the involved autosome, some of which could be sex determination related, creating a new balance between sex chromosomes and autosomes is discussed.

From the Origin of Sex-Determining Factors to the Evolution of Sex-Determining Systems

This perspective emphasizes the importance of both genetic and nongenetic causes in evolution of sex determination and may help to generate predictions with respect to the evolutionary patterns of sex-determining systems and the underlying diversity of developmental and genetic regulatory networks.

Experimenting with sex: four approaches to the genetics of sex reversal before 1950

  • M. Dietrich
  • Psychology
    History and philosophy of the life sciences
  • 2016
The comparison of four researchers and their experimental systems reveals how those different systems mediated their understanding of genetic phenomena, and influenced their interpretations of sex reversal.

Inexorable spread: inexorable death? The fate of neo-XY chromosomes of grasshoppers

Although neo-XY chromosomes of grasshoppers maybe a useful model to explain the spread of a new chromo-somal rearrangement, they are not a predictive example of sex-chromosome evolution and recycling.

Anticoagulant factor V: factors affecting the integration of novel scientific discoveries into the broader framework.

  • M. LaBonte
  • Physics
    Studies in history and philosophy of biological and biomedical sciences
  • 2014

Genetics and Epigenetics: A Historical Overview

Genetics and epigenetics are introduced to the non-expert reader and the significance of major discoveries will be explained and their impact on the understanding of epigenetic mechanisms in health and disease will be discussed.

Graphical and Computationally Intensive Techniques for Presenting and Disseminating Information About the Genetics of Disease

How information gathering and representation broadened steadily to accommodate genetic diagnostic tests is shown, which leads to an examination of the capacity of computational genetics and genomics to generate working models of what causes disease.

References