Mai1p is essential for maturation of proaminopeptidase I but not for autophagy.

@article{Barth2002Mai1pIE,
  title={Mai1p is essential for maturation of proaminopeptidase I but not for autophagy.},
  author={Henning Barth and Khuyen Meiling-Wesse and Ulrike D Epple and Michael Thumm},
  journal={FEBS letters},
  year={2002},
  volume={512 1-3},
  pages={173-9}
}
We here identify Mai1p, a homologue of the autophagy protein Aut10p, as a novel component essential for proaminopeptidase I (proAPI) maturation under non-starvation conditions. In mai1Delta cells mature vacuolar proteinases are detectable and vacuolar acidification is normal. In mai1Delta cells autophagy occurs, though at a somewhat reduced level. This is indicated by proAPI maturation during starvation and accumulation of autophagic bodies during starvation with phenylmethylsulfonyl fluoride… CONTINUE READING

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