Magnolol reduces bleomycin-induced rodent lung fibrosis.

@article{Zhang2015MagnololRB,
  title={Magnolol reduces bleomycin-induced rodent lung fibrosis.},
  author={Xiangfeng Zhang and Han Huang and Huijuan Chang and Xiuhong Jin},
  journal={International journal of clinical and experimental medicine},
  year={2015},
  volume={8 9},
  pages={15450-7}
}
Magnolol, a compound extracted from the Chinese medicinal herb Magnolia officinalis, has been proved to exert multiple pharmacological effects, including anti-oxidant and anti-inflammation activities. In this study, how it influenced bleomycin-induced lung fibrosis of rats was investigated. A single intratracheal instillation of bleomycin (5 mg/Kg, sacrificed 7 and 28 days post bleomycin instillation) caused body weight decrease and lung indices increase. Hodroxyproline content, myeloperoxidase… CONTINUE READING

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