Magnolol inhibits Streptococcus suis-induced inflammation and ROS formation via TLR2/MAPK/NF-κB signaling in RAW264.7 cells.

@article{Zhang2018MagnololIS,
  title={Magnolol inhibits Streptococcus suis-induced inflammation and ROS formation via TLR2/MAPK/NF-$\kappa$B signaling in RAW264.7 cells.},
  author={Lin Zhang and Jinli Wang and W Xu and Yingxian Sun and Ju-yeon You and H. Lu and Y T Song and J Wei and Lijing Li},
  journal={Polish journal of veterinary sciences},
  year={2018},
  volume={21 1},
  pages={
          111-118
        }
}
  • L. Zhang, J. Wang, +6 authors L. Li
  • Published 2018
  • Medicine, Biology
  • Polish journal of veterinary sciences
Our previous studies have shown that Magnolol (Mag) improves the symptoms and decreases the levels of cytokines during infection induced by Streptococcus suis (S. suis) in mice. Although some reports show that Mag inhibits lipopolysaccharide-induced inflammatory responses via downregulating mitogen-activated protein kinases (MAPK) and nuclear factor-κB (NF-κB) signaling pathways, the molecular mechanisms underlying Mag-mediated inhibition of S. suis-induced inflammatory responses are poorly… Expand
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