Magnolol ameliorates lipopolysaccharide-induced acute lung injury in rats through PPAR-γ-dependent inhibition of NF-kB activation.

@article{Lin2015MagnololAL,
  title={Magnolol ameliorates lipopolysaccharide-induced acute lung injury in rats through PPAR-γ-dependent inhibition of NF-kB activation.},
  author={Ming-Hsien Lin and Meng-Chuan Chen and T Chen and Heng-Yuan Chang and T C Chou},
  journal={International immunopharmacology},
  year={2015},
  volume={28 1},
  pages={270-8}
}
Acute lung injury (ALI) has a high morbidity and mortality rate due to the serious inflammation and edema occurred in lung. Magnolol extracted from Magnolia officinalis, has been reported to exhibit anti-inflammatory, and antioxidant activities. Peroxisome proliferator-activated receptors (PPARs) are known to exert a cytoprotective effect against cellular… CONTINUE READING