Magnitude of virologic blips is associated with a higher risk for virologic rebound in HIV-infected individuals: a recurrent events analysis.

@article{Grennan2012MagnitudeOV,
  title={Magnitude of virologic blips is associated with a higher risk for virologic rebound in HIV-infected individuals: a recurrent events analysis.},
  author={J Troy Grennan and Mona Loutfy and Desheng Su and P. Richard Harrigan and Curtis N. Cooper and Marina B Klein and Nim{\^a} Machouf and Julio S. G. Montaner and Sean B Rourke and Christos M. Tsoukas and Bob Hogg and Janet M. Raboud},
  journal={The Journal of infectious diseases},
  year={2012},
  volume={205 8},
  pages={1230-8}
}
BACKGROUND The importance of human immunodeficiency virus (HIV) blip magnitude on virologic rebound has been raised in clinical guidelines relating to viral load assays. METHODS Antiretroviral-naive individuals initiating combination antiretroviral therapy (cART) after 1 January 2000 and achieving virologic suppression were studied. Negative binomial models were used to identify blip correlates. Recurrent event models were used to determine the association between blips and rebound by… CONTINUE READING
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