Magnitude of the second gas effect on arterial sevoflurane partial pressure.

@article{Peyton2008MagnitudeOT,
  title={Magnitude of the second gas effect on arterial sevoflurane partial pressure.},
  author={Philip J Peyton and Maryam Horriat and Gavin J. B. Robinson and Robert Pierce and Bruce R. Thompson},
  journal={Anesthesiology},
  year={2008},
  volume={108 3},
  pages={
          381-7
        }
}
BACKGROUND A number of studies have demonstrated a faster rate of increase in end-expired partial pressure as a fraction of inspired (Pa/Pi) for volatile agents in the presence of high concentrations of nitrous oxide, consistent with the second gas effect. However, no study has demonstrated a similar effect on arterial blood concentrations. METHODS The authors compared arterial and end-tidal partial pressures of sevoflurane (Pa/Pisevo and Pa/Pisevo) in 14 patients for 30 min after… CONTINUE READING

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