Magnitude of effect of lithium in short-term efficacy studies of moderate to severe manic episode.

@article{Storosum2007MagnitudeOE,
  title={Magnitude of effect of lithium in short-term efficacy studies of moderate to severe manic episode.},
  author={Jitschak G. Storosum and Tamar D Wohlfarth and Aart H. Schene and Andr{\'e} J A Elferink and Barbara J van Zwieten and Wim van den Brink},
  journal={Bipolar disorders},
  year={2007},
  volume={9 8},
  pages={793-8}
}
OBJECTIVES To provide an accurate estimation of the magnitude of effect of lithium in short-term efficacy studies conducted in patients with moderate to severe manic episode. METHODS All placebo-controlled randomized studies submitted to the Medicines Evaluation Board (MEB) in which lithium was used as the third study arm were selected for the meta-analysis. The studies were part of registration files submitted to the MEB between the years 1997 and 2005. In addition, Medline and EMbase… CONTINUE READING

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