Magnitude and sources of bias in the detection of mixed strain M. tuberculosis infection

@article{Plazzotta2014MagnitudeAS,
  title={Magnitude and sources of bias in the detection of mixed strain M. tuberculosis infection},
  author={Giacomo Plazzotta and Ted Cohen and Caroline Colijn},
  journal={Journal of theoretical biology},
  year={2014},
  volume={368},
  pages={67 - 73}
}
High resolution tests for genetic variation reveal that individuals may simultaneously host more than one distinct strain of Mycobacterium tuberculosis. Previous studies find that this phenomenon, which we will refer to as "mixed infection", may affect the outcomes of treatment for infected individuals and may influence the impact of population-level interventions against tuberculosis. In areas where the incidence of TB is high, mixed infections have been found in nearly 20% of patients; these… CONTINUE READING

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