Magnetoencephalography-theory, instrumentation, and applications to noninvasive studies of the working human brain

@article{Hmlinen1993MagnetoencephalographytheoryIA,
  title={Magnetoencephalography-theory, instrumentation, and applications to noninvasive studies of the working human brain},
  author={Matti S. H{\"a}m{\"a}l{\"a}inen and Riitta Hari and Risto J. Ilmoniemi and Jukka Knuutila and Olli V. Lounasmaa},
  journal={Reviews of Modern Physics},
  year={1993},
  volume={65},
  pages={413-497}
}
Magnetoencephalography (MEG) is a noninvasive technique for investigating neuronal activity in the living human brain. The time resolution of the method is better than 1 ms and the spatial discrimination is, under favorable circumstances, 2-3 mm for sources in the cerebral cortex. In MEG studies, the weak 10 fT-1 pT magnetic fields produced by electric currents flowing in neurons are measured with multichannel SQUID (superconducting quantum interference device) gradiometers. The sites in the… 

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References

SHOWING 1-10 OF 231 REFERENCES

Magnetoencephalography in the study of epilepsy

Magnetoencephalography: Detection of the Brain's Electrical Activity with a Superconducting Magnetometer

TLDR
The abnormal MEG, including a measurenment of the direct-current component, suggests that the MEG may yield some information which is new and different from that provided by the EEG.

Magnetic localization of neuronal activity in the human brain.

TLDR
Adaptation of activity in human auditory cortex was shown to reveal long-term features with a paradigm that compared response amplitudes for three tones randomly presented, showing the locations of neuronal sources for different tone frequencies could be obtained without moving the recording instrument.

Magnetic field tomography of coherent thalamocortical 40-Hz oscillations in humans.

This paper introduces the use of magnetic field tomography (MFT), a noninvasive technique based on distributed source analysis of magnetoencephalography data, which makes possible the

Noninvasive Functional Localization by Biomagnetic Methods: Part I

TLDR
The generation of biomagnetic fields in living tissue is described and the basic theory of source localization is presented and the most popular models used in various localization studies are presented, and applications are presented.

Techniques for DC Magnetoencephalography

DC shifts are known to occur in association with a number of physiologic phenomena including spreading depression, hypoxia, epilepsy, and hypercapnia and possibly in migraine, closed head injury, and

Magnetoencephalography and epilepsy research.

TLDR
A discussion of the instrumentation based on the superconducting quantum interference device that is used for detecting the magnetic field distribution, the analytical techniques, current research, and future directions of magnetoencephalography in epilepsy research is presented.
...