Magnetization transfer imaging of diffuse axonal injury following experimental brain injury in the pig: characterization by magnetization transfer ratio with histopathologic correlation.

@article{Kimura1996MagnetizationTI,
  title={Magnetization transfer imaging of diffuse axonal injury following experimental brain injury in the pig: characterization by magnetization transfer ratio with histopathologic correlation.},
  author={Hirotaka Kimura and David F. Meaney and Joseph C. McGowan and Robert I. Grossman and Robert E. Lenkinski and D. T. Ross and T K Mcintosh and Thomas A. Gennarelli and Douglas H. Smith},
  journal={Journal of computer assisted tomography},
  year={1996},
  volume={20 4},
  pages={540-6}
}
PURPOSE Our goal was to evaluate the use of the magnetization transfer ratio (MTR) in the detection of diffuse axonal injury (DAI) resulting from traumatic brain injury in a swine model. METHOD DAI was created by applying a nonimpact, coronal plane, rotational acceleration to the heads of miniature swine (n = 4). GE imaging was performed with and without off-resonance MT saturation. Histologic correlation of axonal injury with MRI was performed 7 days postinjury. Thirty-one subcortical white… CONTINUE READING

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