Magnetization transfer imaging for in vivo detection of microstructural tissue changes in aging and dementia: a short literature review.

@article{Seiler2014MagnetizationTI,
  title={Magnetization transfer imaging for in vivo detection of microstructural tissue changes in aging and dementia: a short literature review.},
  author={Stephan Seiler and Stefan Ropele and Reinhold Schmidt},
  journal={Journal of Alzheimer's disease : JAD},
  year={2014},
  volume={42 Suppl 3},
  pages={
          S229-37
        }
}
Magnetization-transfer imaging (MTI), a magnetic resonance imaging acquisition protocol, can detect microstructural brain tissue changes by assessing the magnetization exchange between tissue water and protons bound to macromolecules. This short literature review summarizes results of previous MTI studies in normal aging, cerebral small vessel disease, and Alzheimer's disease (AD). During normal aging, the magnetization transfer ratio (MTR), a measure for the magnitude of magnetization transfer… CONTINUE READING