Magnetization transfer histograms in clinically isolated syndromes suggestive of multiple sclerosis.

@article{Fernando2005MagnetizationTH,
  title={Magnetization transfer histograms in clinically isolated syndromes suggestive of multiple sclerosis.},
  author={Kryshani T M Fernando and Daniel J. Tozer and Katherine A. Miszkiel and R M Gordon and Josephine K Swanton and Catherine M. Dalton and Gareth J. Barker and Gordon T. Plant and Alan J. Thompson and David H. Miller},
  journal={Brain : a journal of neurology},
  year={2005},
  volume={128 Pt 12},
  pages={
          2911-25
        }
}
In established multiple sclerosis, magnetization transfer ratio (MTR) histograms reveal abnormalities of normal-appearing white matter (NAWM) and grey matter (NAGM). The aim of this study was to investigate for such abnormalities in a large cohort of patients presenting with clinically isolated syndromes suggestive of multiple sclerosis. Magnetization transfer imaging was performed on 100 patients (67 women, 33 men, median age 32 years) a mean of 19 weeks (SD 3.8, range 12-33 weeks) after… CONTINUE READING

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