Magnetization transfer effects in MR-detected multiple sclerosis lesions: comparison with gadolinium-enhanced spin-echo images and nonenhanced T1-weighted images.

@article{Hiehle1995MagnetizationTE,
  title={Magnetization transfer effects in MR-detected multiple sclerosis lesions: comparison with gadolinium-enhanced spin-echo images and nonenhanced T1-weighted images.},
  author={J F Hiehle and Robert I. Grossman and K N Ramer and Francisco Gonz{\'a}lez-Scarano and Jeffrey A. Cohen},
  journal={AJNR. American journal of neuroradiology},
  year={1995},
  volume={16 1},
  pages={69-77}
}
PURPOSE To define the relationship between magnetization transfer and blood-brain-barrier breakdown in multiple sclerosis lesions using gadolinium enhancement as an index of the latter. METHODS Two hundred twenty lesions (high-signal abnormalities on T2-weighted images) in 35 multiple sclerosis patients were studied with gadolinium-enhanced spin-echo imaging and magnetization transfer. Lesions were divided into groups having nodular or uniform enhancement, ring enhancement, or no enhancement… CONTINUE READING

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