Magnetization transfer contrast (MTC) and MTC-subtraction: enhancement of cartilage lesions and intracartilaginous degeneration in vitro

@article{Vahlensieck1994MagnetizationTC,
  title={Magnetization transfer contrast (MTC) and MTC-subtraction: enhancement of cartilage lesions and intracartilaginous degeneration in vitro},
  author={Martin Vahlensieck and Frank Dombrowski and Claudia Leutner and U. F. Wagner and Maximilian Reiser},
  journal={Skeletal Radiology},
  year={1994},
  volume={23},
  pages={535-539}
}
Human articular cartilage from 16 cadaveric or amputated knees was studied using standard magnetic resonance imaging (MRI), on-resonance magnetization transfer contrast (MTC) and MTC-subtraction MRI. Results were compared with subsequent macroscopic and histopathological findings. MTC-subtraction and T2-weighted spin-echo images visualized cartilaginous surface defects with high sensitivity and specificity. MTC and T2-weighted spin-echo images revealed intra-cartilaginous signal loss without… CONTINUE READING