Magnetization exchange in capillaries by microcirculation affects diffusion-controlled spin-relaxation: a model which describes the effect of perfusion on relaxation enhancement by intravascular contrast agents.

@article{Bauer1996MagnetizationEI,
  title={Magnetization exchange in capillaries by microcirculation affects diffusion-controlled spin-relaxation: a model which describes the effect of perfusion on relaxation enhancement by intravascular contrast agents.},
  author={Wolfgang R. Bauer and K. H. Hiller and F Roder and Eberhard Rommel and Georg Ertl and Axel Haase},
  journal={Magnetic resonance in medicine},
  year={1996},
  volume={35 1},
  pages={43-55}
}
The effect of perfusion on relaxation time in tissue has only been considered for first-pass kinetics of NMR-signal after application of contrast agents. The importance of perfusion on relaxation has not yet been studied for steady state conditions, i.e., when the intravascular relaxation rate is constant in time. The aim of this study is to develop a model in which T1 relaxation is derived as a function of perfusion and intracapillary volume fraction (regional blood volume). Tissue is… CONTINUE READING

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