Magnetic semipermeable aqueous polyethyleneimine microcapsules for monitoring N-nitrosating species in the gastrointestinal tract.

Abstract

Magnetic polyethyleneimine (PEI) microcapsules have been developed for trapping electrophilic intermediates in the gastrointestinal (GI) tract. The N-nitrosation of these microcapsules at acid pH was found to be linearly dependent on nitrite concentration, without a pH maximum and with efficient conversion to N-nitrosated products which were detected by a… (More)

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