Magnetic resonance tracking of transplanted stem cells in rat brain and spinal cord.

@article{Sykov2006MagneticRT,
  title={Magnetic resonance tracking of transplanted stem cells in rat brain and spinal cord.},
  author={Eva Sykov{\'a} and Pavla Jendelov{\'a}},
  journal={Neuro-degenerative diseases},
  year={2006},
  volume={3 1-2},
  pages={62-7}
}
BACKGROUND Magnetic resonance imaging provides a noninvasive method to study the fate of transplanted cells in vivo. OBJECTIVE We studied the fate of embryonic and mesenchymal stem cells labeled with iron oxide nanoparticles (Endorem) and human CD34+ cells labeled with magnetic MicroBeads (Miltenyi) in rats with a cortical or spinal cord lesion. METHODS Cells were grafted intracerebrally, contralaterally to a cortical photochemical lesion, or injected intravenously. RESULTS During the 1st… CONTINUE READING