Magnetic resonance studies of intramuscular interferon beta-1a for relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group.

@article{Simon1998MagneticRS,
  title={Magnetic resonance studies of intramuscular interferon beta-1a for relapsing multiple sclerosis. The Multiple Sclerosis Collaborative Research Group.},
  author={Jack Simon and Lawrence D. Jacobs and M K Campion and Karl E Wende and N A Simonian and Diane L. Cookfair and Richard A. Rudick and Robert M. Herndon and John R Richert and Andres M. Salazar and Jamiee Alam and Jill S Fischer and Donald E. Goodkin and Carl V. Granger and M Lajaunie and A L Martens-Davidson and Marita Meyer and Jeanelle Leigh Sheeder and Kyungchan Choi and Ann L. Scherzinger and D M Bartoszak and Dennis N. Bourdette and J Braiman and Carol M. Brownscheidle and Ruth H. Whitham},
  journal={Annals of neurology},
  year={1998},
  volume={43 1},
  pages={79-87}
}
The Multiple Sclerosis Collaborative Research Group trial was a double-blind, randomized, multicenter, phase III, placebo-controlled study of interferon beta-1a (IFNbeta-1a; AVONEX) in relapsing forms of multiple sclerosis. Initial magnetic resonance imaging results have been published; this report provides additional results. Treatment with IFNbeta-1a, 30 microg once weekly by intramuscular injection, resulted in a significant decrease in the number of new, enlarging, and new plus enlarging T2… CONTINUE READING
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