Magnetic resonance signal abnormalities in asymptomatic individuals: their incidence and functional correlates.

@article{Fazekas1989MagneticRS,
  title={Magnetic resonance signal abnormalities in asymptomatic individuals: their incidence and functional correlates.},
  author={Franz Fazekas},
  journal={European neurology},
  year={1989},
  volume={29 3},
  pages={164-8}
}
MR signal abnormalities were assessed in 87 symptom-free volunteers (31-83 years of age) and correlated with cerebrovascular risk factors, cerebral blood flow and glucose metabolism. Lesions in the subcortical and deep white matter increased from 11% in the 4th decade to 83% in subjects over 70 years of age, and were detected significantly more often in individuals with cerebrovascular risk factors (p less than 0.01). They were associated with lower slow-compartmental flow (p less than 0.05… CONTINUE READING