Magnetic resonance microscopy of iron in the basal forebrain cholinergic structures of the aged mouse lemur.

@article{Gilissen1999MagneticRM,
  title={Magnetic resonance microscopy of iron in the basal forebrain cholinergic structures of the aged mouse lemur.},
  author={Emmanuel P E Gilissen and Russell E. Jacobs and John M. Allman},
  journal={Journal of the neurological sciences},
  year={1999},
  volume={168 1},
  pages={21-7}
}
Increased non-heme iron levels in the brain of Alzheimer's disease (AD) patients are higher than the levels observed in age matched normal subjects. Iron level in structures that are highly relevant for AD, such as the basal forebrain, can be detected post mortem with histochemistry. Because of the small size of these structures, in vivo MR detection is very difficult at conventional field magnets (1.5 and 4 T). In this study, we observed iron deposits with histochemistry and MR microscopy at… CONTINUE READING

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