Magnetic resonance imaging surrogates of multiple sclerosis pathology and their relationship to central nervous system atrophy.

@article{Meier2004MagneticRI,
  title={Magnetic resonance imaging surrogates of multiple sclerosis pathology and their relationship to central nervous system atrophy.},
  author={Dominik S. Meier and Howard L Weiner and Samia J Khoury and Charles R. G. Guttmann},
  journal={Journal of neuroimaging : official journal of the American Society of Neuroimaging},
  year={2004},
  volume={14 3 Suppl},
  pages={
          46S-53S
        }
}
This article focuses on the various magnetic resonance imaging metrics currently used in multiple sclerosis and discusses how they relate to central nervous system atrophy. The authors discuss the significance of T2 lesion burden, gray matter damage, T1 hypointense lesions (black holes), contrast-enhanced lesions, magnetization transfer imaging, diffusion imaging, and magnetic resonance spectroscopy. These magnetic resonance imaging surrogates exhibit different sensitivities for each of the… CONTINUE READING