Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study.

@article{Albers2006MagneticRI,
  title={Magnetic resonance imaging profiles predict clinical response to early reperfusion: the diffusion and perfusion imaging evaluation for understanding stroke evolution (DEFUSE) study.},
  author={Gregory W. Albers and Vincent N Thijs and Lawrence R. Wechsler and Stephanie Kemp and Gottfried Schlaug and Elaine J Skalabrin and Roland Bammer and Wataru Kakuda and Maarten G Lansberg and Ashfaq Shuaib and William M. L. Coplin and Scott Hamilton and Michael E. Moseley and M P Marks},
  journal={Annals of neurology},
  year={2006},
  volume={60 5},
  pages={
          508-17
        }
}
OBJECTIVE To determine whether prespecified baseline magnetic resonance imaging (MRI) profiles can identify stroke patients who have a robust clinical response after early reperfusion when treated 3 to 6 hours after symptom onset. METHODS We conducted a prospective, multicenter study of 74 consecutive stroke patients admitted to academic stroke centers in North America and Europe. An MRI scan was obtained immediately before and 3 to 6 hours after treatment with intravenous tissue plasminogen… CONTINUE READING
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