Magnetic resonance imaging of the pancreas and pancreatic tumors in a mouse orthotopic model of human cancer.

@article{Grimm2003MagneticRI,
  title={Magnetic resonance imaging of the pancreas and pancreatic tumors in a mouse orthotopic model of human cancer.},
  author={Jan Grimm and Andreas Potthast and Andreas Wunder and Anna Moore},
  journal={International journal of cancer},
  year={2003},
  volume={106 5},
  pages={806-11}
}
Pancreatic adenocarcinoma has a rising incidence and a very poor survival rate. To develop new treatment strategies, extensive research is performed on animal models of pancreatic cancer. Orthotopic pancreatic tumors models, where the tumor is implanted into the pancreas, resemble the human disease more closely than subcutaneous tumor models, yet are difficult to monitor. In our study we report a magnetic resonance imaging (MRI) approach to visualize the pancreas in mice and to monitor… CONTINUE READING

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