Magnetic resonance imaging correlates of clinical outcomes in early multiple sclerosis.

@article{Maghzi2014MagneticRI,
  title={Magnetic resonance imaging correlates of clinical outcomes in early multiple sclerosis.},
  author={A H Maghzi and Nisha R Revirajan and Laura J. Julian and Rebecca I. Spain and E M Mowry and Shuang Liu and Chengshi Jin and Ari J Green and Charles E Mcculloch and Daniel Pelletier and Emmanuelle L Waubant},
  journal={Multiple sclerosis and related disorders},
  year={2014},
  volume={3 6},
  pages={720-7}
}
OBJECTIVES To study the association between changes in brain magnetic resonance imaging (MRI) and clinical outcomes in early MS. METHODS MS patients within 12 months of onset were enrolled and followed up to 3 years. Clinical measures included Symbol Digit Modalities Test (SDMT), MS Functional Composite (MSFC) and low contrast letter acuity (LCLA). MRI outcomes included brain volume changes measured by SIENA and SIENAX normalized measurements [brain parenchymal volume (BPV), normal-appearing… CONTINUE READING
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