Magnetic resonance imaging and spectroscopy of the periarticular inflammatory soft-tissue changes in experimental arthritis of the rat.

@article{Terrier1985MagneticRI,
  title={Magnetic resonance imaging and spectroscopy of the periarticular inflammatory soft-tissue changes in experimental arthritis of the rat.},
  author={F. Terrier and Hedvig Hricak and Didier Revel and Charles E. Alpers and Ch. Reinhold and Jon Levine and Harry K. Genant},
  journal={Investigative radiology},
  year={1985},
  volume={20 8},
  pages={813-23}
}
Arthritis was induced in rats by intradermal injection of Freund's complete adjuvant. MRI was performed with a resistive imager operating at 0.35 T. A spin echo (SE) technique with TR = 0.5 and 2.0 seconds, TE = 28 and 56 msec was used. Transaxial images of hindpaws and knees were obtained at different times after injection of adjuvant. In vitro proton spectroscopy of normal and arthritic hindpaws was also performed. Histologic confirmation was obtained in each case. Inflammatory soft-tissue… CONTINUE READING

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