Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: a meta-analysis.

@article{Kitayama2005MagneticRI,
  title={Magnetic resonance imaging (MRI) measurement of hippocampal volume in posttraumatic stress disorder: a meta-analysis.},
  author={Noriyuki Kitayama and Viola Vaccarino and Michael Kutner and Paul S. Weiss and J. Douglas Bremner},
  journal={Journal of affective disorders},
  year={2005},
  volume={88 1},
  pages={
          79-86
        }
}
BACKGROUND Studies in animals showed that the hippocampus, a brain area involved in learning and memory, is sensitive to stress. Although several MRI studies showed smaller hippocampal volume in adults with chronic PTSD, others did not show significant differences from controls. These studies are typified by small sample sizes which may limit the ability to show significant differences. We therefore performed a meta-analytic study of all of these studies to clarify the role of hippocampal… CONTINUE READING
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