Magnetic resonance imaging (MRI) detection of the murine brain response to light: temporal differentiation and negative functional MRI changes.

@article{Huang1996MagneticRI,
  title={Magnetic resonance imaging (MRI) detection of the murine brain response to light: temporal differentiation and negative functional MRI changes.},
  author={William M Huang and I Plyka and Hui-yun Li and Eli Michael Eisenstein and Nora D. Volkow and Charles S. Springer},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1996},
  volume={93 12},
  pages={6037-42}
}
Using a 9.4 T MRI instrument, we have obtained images of the mouse brain response to photic stimulation during a period between deep anesthesia and the early stages of arousal. The large image enhancements we observe (often >30%) are consistent with literature results extrapolated to 9.4 T. However, there are also two unusual aspects to our findings. (i) The visual area of the brain responds only to changes in stimulus intensity, suggesting that we directly detect operations of the M visual… CONTINUE READING
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