Magnetic iron oxide nanoparticles induce autophagy preceding apoptosis through mitochondrial damage and ER stress in RAW264.7 cells.

Abstract

Magnetic nanoparticles have been widely used in a broad range of disciplines owing to their unique properties. However, many unexpected risks have been reported in their use. In this study, we investigated the uptake process and toxic mechanism of magnetic iron oxide nanoparticles (M-FeNPs) using RAW264.7 cells, a murine peritoneal macrophage cell line. M… (More)
DOI: 10.1016/j.tiv.2014.07.010

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@article{Park2014MagneticIO, title={Magnetic iron oxide nanoparticles induce autophagy preceding apoptosis through mitochondrial damage and ER stress in RAW264.7 cells.}, author={Eun-Jung Park and Dong-Hyuk Choi and Younghun Kim and Eun-Woo Lee and Jaewhan Song and Myung-Haing Cho and Jae-Ho Kim and Sang-Wook Kim}, journal={Toxicology in vitro : an international journal published in association with BIBRA}, year={2014}, volume={28 8}, pages={1402-12} }