Magnetic field intensified bi-enzyme system with in situ cofactor regeneration supported by magnetic nanoparticles.

@article{Zheng2013MagneticFI,
  title={Magnetic field intensified bi-enzyme system with in situ cofactor regeneration supported by magnetic nanoparticles.},
  author={Muqing Zheng and Zhiguo Su and Xiaoyuan Ji and Guanghui Ma and Ping Wang and Songping Zhang},
  journal={Journal of biotechnology},
  year={2013},
  volume={168 2},
  pages={212-7}
}
Efficient dynamic interactions among cofactor, enzymes and substrate molecules are of primary importance for multi-step enzymatic reactions with in situ cofactor regeneration. Here we showed for the first time that the above dynamic interactions could be significantly intensified by exerting an external alternating magnetic field on magnetic nanoparticles-supported multi-enzymatic system so that the inter-particle collisions due to Brownian motion of nanoparticles could be improved. To that end… CONTINUE READING
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