Magnetic field activated drug delivery using thermodegradable azo-functionalised PEG-coated core-shell mesoporous silica nanoparticles.

Abstract

Core-shell Fe3O4@SiO2 mesoporous silica nanoparticles coated with a new thermodegradable polymer allowed the release of a model drug through heating caused by a high frequency oscillating magnetic field. The thermodegradable polymer was made of poly(ethylene glycol) (PEG) functionalised with azo bonds that break with an elevation of temperature.

DOI: 10.1039/c5nr03777h
0100200201520162017
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@article{SaintCricq2015MagneticFA, title={Magnetic field activated drug delivery using thermodegradable azo-functionalised PEG-coated core-shell mesoporous silica nanoparticles.}, author={Philippe Saint-Cricq and Stephanie Deshayes and Jeffrey I Zink and Andrea M Kasko}, journal={Nanoscale}, year={2015}, volume={7 31}, pages={13168-13172} }