Magnetic Resonance Spectroscopy of Tumors : Detection of Ammonium and Trimethylamine Metabolites in the Murine Radiation Induced Fibrosarcoma I 1

Abstract

The in vivo I4N nuclear magnetic resonance spectra of s.c. implanted murine radiation induced fibrosarcomas (RIF-1) display narrow reso nances assignable to betaine and other trimethylamines and broad reso nances due to amino acids and peptides. In 19 of the 41 tumors studied a distinct resonance from the ammonium ion is detectable. The accumu lation of… (More)

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