Magnetic Resonance Spectroscopy in Clinical Oncology
@article{Golder2004MagneticRS, title={Magnetic Resonance Spectroscopy in Clinical Oncology}, author={Werner A. Golder}, journal={Oncology Research and Treatment}, year={2004}, volume={27}, pages={304 - 309} }
The combination of magnetic resonance spectroscopy (MRS) and imaging (MRI) has led to mapping metabolites from normal and neoplastic tissue within the time limits of a routine study. MRSI (magnetic resonance spectroscopy imaging) detects metabolites that contain protons, phosphorus, fluorine, or other nuclei. The uniqueness of the information available in vivo and in a non-invasive manner encouraged radiologists and oncologists to apply MRSI in research and clinical practice. Both 1H- and 31P…
29 Citations
In vivo magnetic resonance spectroscopy in cancer.
- Biology, ChemistryAnnual review of biomedical engineering
- 2005
Tissue choline has proven to be a tumor biomarker that is significantly affected by anticancer therapies and is focused on in this review on the latter applications of in vivo MRS.
Feasibility of In vivo Proton Magnetic Resonance Spectroscopy for Lung Cancer
- Medicine, Physics
- 2012
In vivo proton MRS method using a single-voxel respiration-triggered point-resolved spectroscopic sequence is feasible in obtaining the MR spectra of lung cancer because these spectra were analyzable and high success rate was shown in this study although there was the limitation of small patient group.
Metabolic brain imaging by magnetic resonance
- Biology, Medicine
- 2006
The methods for obtaining metabolic measurements in vivo by MRS that can be combined with any of these MR methods are discussed, including single voxel MRS, which is a novel adaption of the first method.
Metabolic profiling of human brain metastases using in vivo proton MR spectroscopy at 3T
- MedicineBMC Cancer
- 2007
MRS determined metabolic profiles analysed by PCA and PLS might give valuable clinical information when planning and evaluating the treatment of brain metastases, and also when deciding to terminate further therapies.
Clinical 1h magnetic resonance spectroscopy of brain metastases at 1.5T and 3T
- Medicine, PhysicsActa radiologica
- 2006
SNR and spectral resolution were improved at higher magnetic field strength, especially with TE 144 ms, including spectra from patients with heterogeneous brain tumors, however, differences in the defined effective VOI, particularly at short echo time, reduced the expected effect of increased magnetic fieldstrength on the measured SNR.
Imaging of brain tumors: MR spectroscopy and metabolic imaging.
- MedicineNeuroimaging clinics of North America
- 2010
In the assessment of supratentorial glioma grade: the combined role of multivoxel proton MR spectroscopy and diffusion tensor imaging.
- MedicineClinical radiology
- 2011
Evaluating pH in the Extracellular Tumor Microenvironment Using CEST MRI and Other Imaging Methods.
- BiologyAdvances in radiology
- 2015
A comprehensive overview of methods for measuring tumor pHe is provided, including recently developed methods that use chemical exchange saturation transfer MRI that combines some advantages of MR spectroscopy and imaging.
Investigation of compressed-sensing for acceleration of magnetic resonance spectroscopic imaging
- Physics
- 2016
Results suggest that CS-MRSI can reduce scan duration by up to a factor of 5 whilst simultaneously eliminating ringing artefacts and increasing spatial resolution compared with conventionally filtered MRSI, suggesting that CS could greatly increase the clinical utility of MRSi.
Utilization of advanced imaging technologies for target delineation in radiation oncology.
- Medicine, PhysicsJournal of the American College of Radiology : JACR
- 2009
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