Magnetic Resonance Spectroscopy as a Tool for Assessing Macromolecular Structure and Function in Living Cells.

@article{Li2017MagneticRS,
  title={Magnetic Resonance Spectroscopy as a Tool for Assessing Macromolecular Structure and Function in Living Cells.},
  author={Conggang Li and Jiajing Zhao and Kai Cheng and Yuwei Ge and Qiong Wu and Yansheng Ye and Guohua Xu and Zeting Zhang and Wenwen Zheng and Xu Zhang and Xin Zhou and Gary J Pielak and Maili Liu},
  journal={Annual review of analytical chemistry},
  year={2017},
  volume={10 1},
  pages={
          157-182
        }
}
Investigating the structure, modification, interaction, and function of biomolecules in their native cellular environment leads to physiologically relevant knowledge about their mechanisms, which will benefit drug discovery and design. In recent years, nuclear and electron magnetic resonance (NMR) spectroscopy has emerged as a useful tool for elucidating the structure and function of biomacromolecules, including proteins, nucleic acids, and carbohydrates in living cells at atomic resolution. In… CONTINUE READING

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