Magnetic Resonance Imaging of Brain Edema in the Neonatal Rat: A Comparison of Short and Long Term Hypoxia-ischemia

@article{Rumpel1995MagneticRI,
  title={Magnetic Resonance Imaging of Brain Edema in the Neonatal Rat: A Comparison of Short and Long Term Hypoxia-ischemia},
  author={Helmut Rumpel and Reto Buchli and Jochen Gehrmann and Adriano Aguzzi and Oscar E Illi and Ernst Martin},
  journal={Pediatric Research},
  year={1995},
  volume={38},
  pages={113-118}
}
ABSTRACT: Diffusion-weighted and transversal relaxation time (T2)-weighted magnetic resonance imaging were used to study the relationship between the duration of hypoxia-ischemia [unilateral common carotid artery (CCA) ligation and exposure to 8% oxygen] and the in vivo visualization of brain edema in 7-d-old rats. After CCA ligation, 35 animals were divided into five groups according to the length of exposure to 8% oxygen: no exposure (n = 9), 15 min (n = 12), 30 min (n = 5), and 1 h (n = 9… CONTINUE READING