Magnetic-Resonance-Imaging Texture Analysis Predicts Early Progression in Rectal Cancer Patients Undergoing Neoadjuvant Chemoradiation

  title={Magnetic-Resonance-Imaging Texture Analysis Predicts Early Progression in Rectal Cancer Patients Undergoing Neoadjuvant Chemoradiation},
  author={Valerio Nardone and Alfonso Reginelli and Fernando Scala and Salvatore Francesco Carbone and Maria Antonietta Mazzei and Lucio Sebaste and Tommaso Carfagno and Giuseppe Battaglia and Pierpaolo Pastina and Pierpaolo Correale and Paolo Tini and Gianluca Pellino and Salvatore Cappabianca and Luigi Pirtoli},
  journal={Gastroenterology Research and Practice},
Background We hypothesized that texture analysis (TA) from the preoperative MRI can predict early disease progression (ePD), defined as the percentage of patients who relapsed or showed distant metastasis within three months from the radical surgery, in patients with locally advanced rectal cancer (LARC, stage II and III, AJCC) undergoing neoadjuvant chemoradiotherapy (C-RT). Methods This retrospective monoinstitutional cohort study included 49 consecutive patients in total with a newly… 

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