Magnetic Resonance–Guided Focused Ultrasound for Patients With Painful Bone Metastases: Phase III Trial Results

@inproceedings{Hurwitz2014MagneticRF,
  title={Magnetic Resonance–Guided Focused Ultrasound for Patients With Painful Bone Metastases: Phase III Trial Results},
  author={Mark David Hurwitz and Pejman Ghanouni and Sergey Vasilevich Kanaev and Dmitri Iozeffi and David Gianfelice and Fiona M. Fennessy and Abraham Kuten and Joshua E. Meyer and Suzanne D Leblang and Ann Roberts and Junsung Choi and James M. Larner and Alessandro Napoli and Vladimir G. Turkevich and Yael Inbar and Clare Mary C. Tempany and Raphael M. Pfeffer},
  booktitle={Journal of the National Cancer Institute},
  year={2014}
}
BACKGROUND Pain due to bone metastases is a common cause of cancer-related morbidity, with few options available for patients refractory to medical therapies and who do not respond to radiation therapy. This study assessed the safety and efficacy of magnetic resonance-guided focused ultrasound surgery (MRgFUS), a noninvasive method of thermal tissue ablation for palliation of pain due to bone metastases. METHODS Patients with painful bone metastases were randomly assigned 3:1 to receive… CONTINUE READING
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