Magnesium sulfate infusion during late gestation does not elicit a peripheral vascular steal and preserves placental perfusion.

Abstract

Despite proven efficacy in interrupting uterine smooth muscle contraction for periods of 24-48 h, a recent clinical study concluded that the adrenergic beta-receptor agonist, ritodrine hydrochloride (Yutopar) had significant detrimental side effects. Our previous preclinical studies have shown that ritodrine reduces placental blood flow via a vascular steal… (More)

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