Magnesium in the gynecological practice: a literature review.

  title={Magnesium in the gynecological practice: a literature review.},
  author={Fabio Parazzini and Mirella Di Martino and Paolo Pellegrino},
  journal={Magnesium research},
  volume={30 1},
A growing amount of evidence suggests that magnesium deficiency may play an important role in several clinical conditions concerning women health such as premenstrual syndrome, dysmenorrhea, and postmenopausal symptoms. A number of studies highlighted a positive correlation between magnesium administration and relief or prevention of these symptoms, thus suggesting that magnesium supplementation may represent a viable treatment for these conditions. Despite this amount of evidence describing… 

Has Menstruation Disappeared? Functional Hypothalamic Amenorrhea—What Is This Story about?

This review of the literature aims to update the current knowledge of functional hypothalamic amenorrhea and underscores the complexity of the disorder, with particular emphasis on the nutritional aspects and potential interventions for restoring balance.

Micronutrient deficiency in menstrual dysfunction among women of reproductive age

Objective. To determine whether inorganic menstrual dysfunction (MD) is associated with magnesium, iron and vitamin D deficiency in women of reproductive age. Materials and methods. The study group

Magnesium Status and Stress: The Vicious Circle Concept Revisited

This review revisits the magnesium and stress vicious circle concept, first introduced in the early 1990s, in light of recent available data, and suggests that stress could increase magnesium loss, causing a deficiency; and in turn, magnesium deficiency could enhance the body’s susceptibility to stress, resulting in a magnesium and Stress vicious circle.

Efficacy and Safety of Magnesium for the Management of Chronic Pain in Adults: A Systematic Review

Future, larger-sized trials with good assay sensitivity and better safety assessment and reporting, as well as careful attention to formulations with optimal bioavailability, will serve to better define the role of magnesium in the management of chronic pain.

Magnesium for the Management of Chronic Noncancer Pain in Adults: Protocol for a Systematic Review

A detailed search on Cochrane Central Register of Controlled Trials, MEDLINE, and EMBASE from their inception until the date the searches are run is expected to identify available high-quality evidence describing the efficacy and safety of magnesium for the treatment of chronic noncancer pain.

Response of Vitamin D after Magnesium Intervention in a Postmenopausal Population from the Province of Granada, Spain

The administration of magnesium resulted in significantly increased vitamin D levels in the intervention group versus the controls (p < 0.05).

Magnesium: Biochemistry, Nutrition, Detection, and Social Impact of Diseases Linked to Its Deficiency

This review offers an overview of recent insights into magnesium from multiple perspectives, starting from a biochemical point of view, at highlighting the risk due to insufficient uptake, at suggesting strategies to reach the recommended dietary reference values, and at focusing on the importance of detecting physiological or pathological levels of magnesium in various body districts.

Magnesium for the Management of Chronic Noncancer Pain in Adults: Protocol for a Systematic Review (Preprint)

A detailed search on Cochrane Central Register of Controlled Trials, MEDLINE, and EMBASE is conducted to identify relevant randomized controlled trials comparing magnesium compared with a placebo for the treatment of chronic noncancer pain to identify high-quality evidence describing the efficacy and safety of magnesium.

The Chronic Use of Magnesium Decreases VEGF Levels in the Uterine Tissue in Rats

Regular magnesium use decreased VEGF levels in uterus and was associated with decreased uterine oxidative stress, demonstrating that chronic magnesium usage may protect the uterine tissue from certain diseases in which angiogenesis is critical.

The Role of Mineral and Trace Element Supplementation in Exercise and Athletic Performance: A Systematic Review

There is little evidence to support the use of MTE supplementation to improve physiological markers of athletic performance, with the possible exception of Iron (in particular, biological situations) and Magnesium as these currently have the strongest quality evidence.



[Therapeutic effects of magnesium in dysmenorrhea].

Primary dysmenorrhea is a common gynaecological symptom complex characterized by a painful syndrome occurring predominantly on the first and the second day of the cycle and associated with

[Magnesium--a new therapeutic alternative in primary dysmenorrhea].

Beside the PG-synthesis and ovulation inhibitors the use of Magnesium is a potential, natural opportunity to treat primary dysmenorrhoea, which is widely free of side effects.

Evaluating the effect of magnesium and magnesium plus vitamin B6 supplement on the severity of premenstrual syndrome

The findings indicated that Mg plus vitamin B6 and placebo has the greatest and the least effect on the mean score of PMS, respectively.

Premenstrual syndrome. Advances in diagnosis and treatment.

  • B. Kessel
  • Psychology, Medicine
    Obstetrics and gynecology clinics of North America
  • 2000

Premenstrual syndrome: A mini review.

Herbal and dietary therapies for primary and secondary dysmenorrhoea.

The efficacy and safety of herbal and dietary therapies for the treatment of primary and secondary dysmenorrhoea when compared to each other, placebo, no treatment or other conventional treatments were determined.

Magnesium deficiency and osteoporosis: animal and human observations.

Magnesium supplementation alleviates premenstrual symptoms of fluid retention.

A daily supplement of 200 mg of Mg (as MgO) reduced mild premenstrual symptoms of fluid retention in the second cycle of administration and Compliance to supplementation was confirmed.