Magnesium enhances adherence and cartilage formation of synovial mesenchymal stem cells through integrins.

@article{Shimaya2010MagnesiumEA,
  title={Magnesium enhances adherence and cartilage formation of synovial mesenchymal stem cells through integrins.},
  author={Masayuki Shimaya and Takeshi Muneta and Shizuko Ichinose and Kiyoshi Tsuji and Ichiro Sekiya},
  journal={Osteoarthritis and cartilage},
  year={2010},
  volume={18 10},
  pages={1300-9}
}
OBJECTIVE We previously reported that more than 60% of synovial mesenchymal stem cells (MSCs) placed on osteochondral defects adhered to the defect within 10 min and promoted cartilage regeneration. The efficiency of adherence is considered to depend on the interaction between cells and extracellular matrix (ECM), in which integrins may play some important roles. Divalent cations such as calcium, magnesium, and manganese may affect functions of integrins, and the integrins may be involved in… CONTINUE READING

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