Magnesium depletion in patients on long-term chlorthalidone therapy for essential hypertension

Abstract

Sixty patients were treated for 1 year for essential uncomplicated hypertension, 30 with beta-blockers alone (BB) and 30 with BB and chlorthalidone (CTD). BB did not affect serum K+ or Mg++. In the BB-group there was a statistically significant trend towards retention of Mg++ in a loading test, but the effect was clinically marginal. BB + CTD reduced serum… (More)
DOI: 10.1007/BF00543964

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@article{Cocco1987MagnesiumDI, title={Magnesium depletion in patients on long-term chlorthalidone therapy for essential hypertension}, author={Giuseppe Cocco and Hans U Iselin and Chiara Strozzi and Bruno Maria Cesana and H. R. Baumeler}, journal={European Journal of Clinical Pharmacology}, year={1987}, volume={32}, pages={335-338} }