Magnesium and chronic fatigue syndrome

  title={Magnesium and chronic fatigue syndrome},
  author={Simon Wessely and Ian S Young and Elisabeth R. Trimble and Caroline Tung Richmond and Charles Shepherd},
  journal={The Lancet},
2 Citations

Magnesium and Oxidative Stress Status in Patients with Chronic Fatigue

It is still not clear whether there is a direct causal link between Mg deficiency, oxidative stress and the resulting disease process or whether these are parallel unrelated phenomena.

Review and Hypothesis: Might Patients with the Chronic Fatigue Syndrome Have Latent Tetany of Magnesium Deficiency

The latent tetany syndrome (LTS) parallels CFS in its neuromuscular and psychiatric manifestations, as well as in inner ear disturbances: vestibular in CFS and FM, as well as in LTS, and increased



Evaluation of amitriptyline in primary fibrositis. A double-blind, placebo-controlled study.

The patients who received amitriptyline improved significantly in their morning stiffness and pain analog scores at 5 and 9 weeks, compared with baseline scores, whereas no changes were noted in these parameters in the placebo group.

A randomized, controlled trial of amitriptyline and naproxen in the treatment of patients with fibromyalgia.

Amitriptyline was associated with significant improvement in all outcome parameters, including patient and physician global assessments, patient pain, sleep difficulties, fatigue on awakening, and tender point score.

High frequency of fibromyalgia in patients with chronic fatigue seen in a primary care practice.

The majority of patients with debilitating chronic fatigue, including those who met criteria for CFS, met the historical and tender point diagnostic criteria for fibromyalgia, and the presence of current musculoskeletal pain will identify those CFS patients who have Fibromyalgia.

Evaluation of body magnesium stores.

It would appear from these results that bone and extracellular fluid magnesium are the major magnesium pools in man increased during magnesium excess and decreased during magnesium depletion.

Old wine in new bottles: neurasthenia and 'ME'.

  • S. Wessely
  • Psychology, Medicine
    Psychological medicine
  • 1990
It is shown that neurasthenia remained popular as long as it was viewed as a non-psychiatric, neurological illness caused by environmental factors which affected successful people and for which the cure was rest.

Enteroviral RNA sequences detected by polymerase chain reaction in muscle of patients with postviral fatigue syndrome.

Persistent enteroviral infection of muscle may occur in some patients with postviral fatigue syndrome and may have an aetiological role.

Magnesium content of mononuclear blood cells.

The magnesium content of mononuclear blood cells may provide a better assessment of intracellular magnesium or total body magnesium status than does measurement of magnesium in plasma or